# Test Scenario 05: Medical Research - Clinical Trial Protocol Development

## 🏢 **Industry Context**: Healthcare/Medical Research
**Role**: Clinical Research Coordinator  
**Task**: Research regulations and best practices for designing Phase II clinical trials

## 📋 **Scenario Description**
You're a clinical research coordinator at a pharmaceutical company developing a new diabetes medication. Your team needs to design a Phase II clinical trial protocol that meets FDA requirements and follows good clinical practice (GCP) guidelines.

## 🎯 **Your Mission (Completely Autonomous)**

### **Step 1: Setup FSS-Mini-RAG**
1. Read the repository README.md to understand how to install FSS-Mini-RAG
2. Follow the installation instructions for your platform
3. Verify the installation works by running `rag-mini --help`

### **Step 2: Gather Research Materials**
Create a folder called `clinical-trial-research` and populate it with relevant documentation:
- FDA clinical trial guidance documents
- ICH Good Clinical Practice guidelines
- IRB/Ethics committee requirements
- Patient safety and adverse event reporting protocols
- Statistical analysis plans for clinical trials

**Sources to explore**:
- FDA.gov clinical trial guidance documents
- International Council for Harmonisation (ICH) guidelines
- Good Clinical Practice training materials
- Clinical research regulatory handbooks
- Biostatistics and clinical trial design resources

### **Step 3: Index and Search**
1. Use FSS-Mini-RAG to index your `clinical-trial-research` folder
2. Perform searches to answer these questions:
   - "What are the FDA requirements for Phase II trial design?"
   - "How should adverse events be classified and reported?"
   - "What statistical power calculations are needed for efficacy endpoints?"
   - "What informed consent elements are required?"
   - "How should patient eligibility criteria be defined?"

### **Step 4: Document Your Findings**
Write your findings in `RESULTS.md` including:
- FDA regulatory requirements for Phase II trials
- Patient safety monitoring and reporting procedures
- Statistical analysis and sample size calculations
- Informed consent and ethical considerations
- Protocol development timeline and milestones

### **Step 5: Evaluation**
Rate FSS-Mini-RAG's effectiveness for:
- Finding specific information across multiple documents
- Searching complex documentation efficiently
- Helping with research and analysis workflows
- Overall usefulness for healthcare/medical research industry applications

## 📁 **Deliverables**
- `clinical-trial-research/` folder with research materials
- `RESULTS.md` with findings and FSS-Mini-RAG evaluation
- Documentation of your search queries and discoveries

## ⏱️ **Expected Duration**: 2-3 hours

## 🎓 **Learning Objectives**
- Test FSS-Mini-RAG with healthcare/medical research industry content
- Evaluate search effectiveness with domain-specific documentation
- Assess usefulness for professional research workflows in healthcare/medical research